The high and increasing global burden of cancer highlights the need for effective implementation of primary cancer prevention programmes targeting modifiable risk factors. However, evidence-based programmes with proven effectiveness in controlled settings often fail when implemented in the real world due to ineffective adaptation and implementation strategies that address context-specific barriers, leading to programme failure and public health inequities. There is a need to provide decision-makers and implementers with tools to effectively adapt and implement evidence-based cancer prevention programmes.

The main objective of the PIECES project is to improve the reach and effectiveness of primary prevention programmes. With a consortium of 15 partners, the project team will develop an innovative toolkit, known as the PCP Integrated Implementation Toolkit (PCP-IT), designed to guide and assist users in selecting, adapting, and implementing cancer prevention programmes. PIECES is structured in two phases: The first phase is aimed at developing the PCP-IT. The second phase involves a comparative case study in multiple locations.